Article Navigation
- < Previous
- Next >
Journal Article
Get access
, Lucas Van Hoof Department of Cardiac Surgery, UZ Leuven , Herestraat 49 , 3000 Leuven, Belgium Search for other works by this author on: Oxford Academic Bert Rooyackers Department of Cardiac Surgery, UZ Leuven , Herestraat 49 , 3000 Leuven, Belgium Search for other works by this author on: Oxford Academic Art Schuermans Department of Cardiac Surgery, UZ Leuven , Herestraat 49 , 3000 Leuven, Belgium Search for other works by this author on: Oxford Academic Jolien Duponselle Department of Cardiac Surgery, UZ Leuven , Herestraat 49 , 3000 Leuven, Belgium Search for other works by this author on: Oxford Academic Alexander Van De Bruaene Department of Cardiovascular Diseases, UZ Leuven , Herestraat 49 , 3000 Leuven, Belgium Search for other works by this author on: Oxford Academic Pieter De Meester Department of Cardiovascular Diseases, UZ Leuven , Herestraat 49 , 3000 Leuven, Belgium Search for other works by this author on: Oxford Academic Els Troost Department of Cardiovascular Diseases, UZ Leuven , Herestraat 49 , 3000 Leuven, Belgium Search for other works by this author on: Oxford Academic Bart Meuris Department of Cardiac Surgery, UZ Leuven , Herestraat 49 , 3000 Leuven, Belgium Search for other works by this author on: Oxford Academic Werner Budts Department of Cardiovascular Diseases, UZ Leuven , Herestraat 49 , 3000 Leuven, Belgium Search for other works by this author on: Oxford Academic Marc Gewillig Department of Pediatric Cardiology, UZ Leuven , Herestraat 49 , 3000 Leuven, Belgium Search for other works by this author on: Oxford Academic
, Willem Flameng Department of Cardiac Surgery, UZ Leuven , Herestraat 49 , 3000 Leuven, Belgium Search for other works by this author on: Oxford Academic Willem Daenen Department of Cardiac Surgery, UZ Leuven , Herestraat 49 , 3000 Leuven, Belgium Search for other works by this author on: Oxford Academic Bart Meyns Department of Cardiac Surgery, UZ Leuven , Herestraat 49 , 3000 Leuven, Belgium Search for other works by this author on: Oxford Academic Peter Verbrugghe Department of Cardiac Surgery, UZ Leuven , Herestraat 49 , 3000 Leuven, Belgium Search for other works by this author on: Oxford Academic Filip Rega Department of Cardiac Surgery, UZ Leuven , Herestraat 49 , 3000 Leuven, Belgium Corresponding author. Department of Cardiac Surgery, UZ Leuven, Herestraat 49, 3000 Leuven, Belgium. Tel: +32-16-344260; e-mail: filip.rega@uzleuven.be (F. Rega). Search for other works by this author on: Oxford Academic
European Journal of Cardio-Thoracic Surgery, Volume 66, Issue 1, July 2024, ezae267, https://doi.org/10.1093/ejcts/ezae267
Published:
11 July 2024
Article history
Received:
20 March 2024
Revision received:
09 June 2024
Published:
11 July 2024
Corrected and typeset:
27 July 2024
- Views
- Article contents
- Figures & tables
- Video
- Audio
- Supplementary Data
-
Cite
Cite
Lucas Van Hoof, Bert Rooyackers, Art Schuermans, Jolien Duponselle, Alexander Van De Bruaene, Pieter De Meester, Els Troost, Bart Meuris, Werner Budts, Marc Gewillig, Willem Flameng, Willem Daenen, Bart Meyns, Peter Verbrugghe, Filip Rega, Long-term outcome after the Ross procedure in 173 adults with up to 25 years of follow-up, European Journal of Cardio-Thoracic Surgery, Volume 66, Issue 1, July 2024, ezae267, https://doi.org/10.1093/ejcts/ezae267
Close
Search
Close
Search
Advanced Search
Search Menu
Abstract
OBJECTIVES
The potential risk of autograft dilatation and homograft stenosis after the Ross procedure mandates lifelong follow-up. This retrospective cohort study aimed to determine long-term outcome of the Ross procedure, investigating autograft and homograft failure patterns leading to reintervention.
METHODS
All adults who underwent the Ross procedure between 1991 and 2018 at the University Hospitals Leuven were included, with follow-up data collected retrospectively. Autograft implantation was performed using the full root replacement technique. The primary end-point was long-term survival. Secondary end-points were survival free from any reintervention, autograft or homograft reintervention-free survival, and evolution of autograft diameter, homograft gradient and aortic regurgitation grade over time.
RESULTS
A total of 173 adult patients (66% male) with a median age of 32 years (range 18–58 years) were included. External support at both the annulus and sinotubular junction was used in 38.7% (67/173). Median follow-up duration was 11.1 years (IQR, 6.4–15.9; 2065 patient-years) with 95% follow-up completeness. There was one (0.6%) perioperative death. Kaplan–Meier estimate for 15-year survival was 91.1% and Ross-related reintervention-free survival was 75.7% (autograft: 83.5%, homograft: 85%). Regression analyses demonstrated progressive neoaortic root dilatation (0.56 mm/year) and increase in homograft gradient (0.72 mmHg/year).
CONCLUSIONS
The Ross procedure has the potential to offer excellent long-term survival and reintervention-free survival. These long-term data further confirm that the Ross procedure is a suitable option in young adults with aortic valve disease which should be considered on an individual basis.
Open in new tabDownload slide
Ross procedure, Reintervention, Pulmonary autograft, Pulmonary homograft
© The Author(s) 2024. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.
This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/pages/standard-publication-reuse-rights)
Subject
Great Vessels Valve Disorders (Acquired Cardiac) Grown-up Congenital Heart Disease Valvular Anomalies (Congenital)
You do not currently have access to this article.
Download all slides
Sign in
Get help with access
Personal account
- Sign in with email/username & password
- Get email alerts
- Save searches
- Purchase content
- Activate your purchase/trial code
- Add your ORCID iD
Sign in Register
Institutional access
- Sign in with a library card
- Sign in with username/password
- Recommend to your librarian
Sign in through your institution
Sign in through your institution
Institutional account management
Sign in as administrator
Get help with access
Institutional access
Access to content on Oxford Academic is often provided through institutional subscriptions and purchases. If you are a member of an institution with an active account, you may be able to access content in one of the following ways:
IP based access
Typically, access is provided across an institutional network to a range of IP addresses. This authentication occurs automatically, and it is not possible to sign out of an IP authenticated account.
Sign in through your institution
Choose this option to get remote access when outside your institution. Shibboleth/Open Athens technology is used to provide single sign-on between your institution’s website and Oxford Academic.
- Click Sign in through your institution.
- Select your institution from the list provided, which will take you to your institution's website to sign in.
- When on the institution site, please use the credentials provided by your institution. Do not use an Oxford Academic personal account.
- Following successful sign in, you will be returned to Oxford Academic.
If your institution is not listed or you cannot sign in to your institution’s website, please contact your librarian or administrator.
Sign in with a library card
Enter your library card number to sign in. If you cannot sign in, please contact your librarian.
Society Members
Society member access to a journal is achieved in one of the following ways:
Sign in through society site
Many societies offer single sign-on between the society website and Oxford Academic. If you see ‘Sign in through society site’ in the sign in pane within a journal:
- Click Sign in through society site.
- When on the society site, please use the credentials provided by that society. Do not use an Oxford Academic personal account.
- Following successful sign in, you will be returned to Oxford Academic.
If you do not have a society account or have forgotten your username or password, please contact your society.
Sign in using a personal account
Some societies use Oxford Academic personal accounts to provide access to their members. See below.
Personal account
A personal account can be used to get email alerts, save searches, purchase content, and activate subscriptions.
Some societies use Oxford Academic personal accounts to provide access to their members.
Viewing your signed in accounts
Click the account icon in the top right to:
- View your signed in personal account and access account management features.
- View the institutional accounts that are providing access.
Signed in but can't access content
Oxford Academic is home to a wide variety of products. The institutional subscription may not cover the content that you are trying to access. If you believe you should have access to that content, please contact your librarian.
Institutional account management
For librarians and administrators, your personal account also provides access to institutional account management. Here you will find options to view and activate subscriptions, manage institutional settings and access options, access usage statistics, and more.
Purchase
Subscription prices and ordering for this journal
Purchasing options for books and journals across Oxford Academic
Short-term Access
To purchase short-term access, please sign in to your personal account above.
Don't already have a personal account? Register
Long-term outcome after the Ross procedure in 173 adults with up to 25 years of follow-up - 24 Hours access
EUR €39.00
GBP £34.00
USD $42.00
Advertisement intended for healthcare professionals
Citations
Views
59
Altmetric
More metrics information
Metrics
Total Views 59
3 Pageviews
56 PDF Downloads
Since 7/1/2024
Month: | Total Views: |
---|---|
July 2024 | 59 |
Citations
Powered by Dimensions
Altmetrics
Email alerts
Article activity alert
Advance article alerts
New issue alert
In progress issue alert
Subject alert
Receive exclusive offers and updates from Oxford Academic
Citing articles via
Google Scholar
-
Most Read
-
Most Cited
More from Oxford Academic
Cardiothoracic Surgery
Medicine and Health
Surgery
Books
Journals
Advertisement intended for healthcare professionals