- By : Alberto Tagliafico
- Medical
Digital Breast Tomosynthesis
Author: Alberto Tagliafico
Publisher: Springer
ISBN: 3319286315
Category : Medical
Languages : en
Pages : 148
Book Description
This book provides a comprehensive description of the screening and clinical applications of digital breast tomosynthesis (DBT) and offers straightforward, clear guidance on use of the technique. Informative clinical cases are presented to illustrate how to take advantage of DBT in clinical practice. The importance of DBT as a diagnostic tool for both screening and diagnosis is increasing rapidly. DBT improves upon mammography by depicting breast tissue on a video clip made of cross‐sectional images reconstructed in correspondence with their mammographic planes of acquisition. DBT results in markedly reduced summation of overlapping breast tissue and offers the potential to improve mammographic breast cancer surveillance and diagnosis. This book will be an excellent practical teaching guide for beginners and a useful reference for more experienced radiologists.
- By : Ygal Haupt
- Medicine (General)
Human Tumor-Derived p53 Mutants: A Growing Family of Oncoproteins
Author: Ygal Haupt
Publisher: Frontiers Media SA
ISBN: 2889199614
Category : Medicine (General)
Languages : en
Pages : 99
Book Description
TP53 gene mutations are present in more than half of all human cancers. The resulting proteins are mostly full-length with a single amino acid change and are abundantly expressed in cancer cells. Some of the mutant p53 proteins gain oncogenic functions (GOF) through which it actively contribute to the aberrant cell proliferation, increased resistance to apoptotic stimuli and ability to metastasize. Gain of function mutant p53 proteins can transcriptionally regulate the expression of a large plethora of target genes. This mainly occurs through the formation of oncogenic transcriptional competent complexes that include mutant p53 protein, known transcription factors, posttranslational modifiers and scaffold proteins. Mutant p53 protein can also transcriptionally regulate the expression of microRNAs, small non-coding RNAs that regulate gene expression at the posttranscriptional level. Each microRNA can putatively target the expression of hundred mRNAs and consequently impact on many cellular functions. Thus, gain of function mutant p53 proteins can exert their oncogenic activities through the modulation of both non-coding and coding regions of human genome. Over the past 3 decades, the regulation of p53 has been extensively studied. However, the regulation of mutant p53 remained largely unexplored. This snapshot focuses on recent discovery of mutant p53 GOF and regulation.
- By : Mario Maggi
- Medical
Hormonal Therapy for Male Sexual Dysfunction
Author: Mario Maggi
Publisher: John Wiley & Sons
ISBN: 047065760X
Category : Medical
Languages : en
Pages : 144
Book Description
Hormonal therapy offers a potentially powerful approach to the treatment of sexual disorders in men. However the interplay of different hormones within different bodily systems is carefully balanced; judicious judgement is required in the therapeutic use of hormones to minimize unwelcome side effects. A better understanding of how hormones work will help the physician to better tailor therapies for improved sexual responses in men. Hormonal Therapy for Male Sexual Dysfunction will provide the rationale for hormonal therapy in male sexual disorders, explaining the language of sexual endocrinology and its application in clinical practice. The aim of this book is to provide a clinical 'in the office' or 'at the bedside' guide to effective patient care for sexual medicine physicians, urologists, gynecologists and other health-care providers in practice and in training. The tone will be practical, not academic. The working assumption is that readers want to know what (and what not) might or should be done, without over emphasis on the why. That said, it is important to review the crucial basic science necessary for effective diagnosis and management, and to provide reminders in the context of the practical chapters. It will not be heavily referenced, in line with a more practical approach. This allows for smoother reading (and also relieves the burden of comprehensive citing from authors). Key evidence (clinical trials, Cochrane or other meta analyses) should be summarized in 'Evidence at a Glance' boxes and key references such as reviews, major papers can be provided in the ‘selected bibliography’ at the end of each chapter. Practical guidance will be provided through: the use of algorithms and guidelines where they are appropriate 'Tips and Tricks' boxes – hints on improving outcomes perhaps via practical technique, patient questioning etc 'Caution' warning boxes – hints on avoiding problems, perhaps via contraindications 'Science Revisited' – quick reminder of the basic science principles necessary for understanding
- By : Heinz Bohmert
- Breast
Breast Cancer
Author: Heinz Bohmert
Publisher: Georg Thieme Verlag
ISBN:
Category : Breast
Languages : en
Pages : 568
Book Description
- By : Lise Aaboen
Starting Up in Business Networks
Author: Lise Aaboen
Publisher: Springer
ISBN: 1137527196
Category : Business & Economics
Languages : en
Pages : 321
Book Description
This book offers a novel perspective on starting-up new business ventures through examining the process by which they become part of the existing business environment. The book highlights the importance of inter-organizational business relationships. Asserting that new ventures need to interact and connect with customers and suppliers, alongside policy actors and universities, Starting up in Business Networks demonstrates how beginning a new venture demands initiating and developing business relationships. Noting a lack of prior research into the process by which start-ups embed into an existing business network, this book presents examples from countries such as Sweden, Italy, the Netherlands and China to analyse the emergence and evolution of start-up business networks.
- By : Joanne Stepaniak
- Cooking
Raising Vegetarian Children
Author: Joanne Stepaniak
Publisher: McGraw Hill Professional
ISBN: 9780658021558
Category : Cooking
Languages : en
Pages : 412
Book Description
This handbook aims to debunk the myth that vegetarian diets provide inadequate nutrition for growing children. Separate chapters address the needs of infants, preschoolers, school-age children, and teenagers. There are lots of child-friendly recipes, and a resources section.
- By : Jens O. Andreasen
- Medical
Textbook and Color Atlas of Traumatic Injuries to the Teeth
Author: Jens O. Andreasen
Publisher: John Wiley & Sons
ISBN: 111916706X
Category : Medical
Languages : en
Pages : 1064
Book Description
Textbook and Color Atlas of Traumatic Injuries to the Teeth, Fifth Edition encompasses the full scope of acute dental trauma, including all aspects of interdisciplinary treatment. This new edition embraces the significant advances made in the subject of dental traumatology since the publication of the previous edition in 2007. Thoroughly updated throughout, it includes eight new chapters, including one chapter focused on the development of bioengineered teeth and another on clinical regenerative endodontics. Providing the theoretical background behind the clinical applications, the text is supplemented by a step-by-step online guide to procedures at www.dentaltraumaguide.org. The book is also filled with full-color illustrations throughout—making it the ultimate guide for anyone treating individuals afflicted with dental injuries caused by traffic accidents, sporting injuries, violent assaults, and other falls, crashes, or injuries. New edition of the definitive reference on dental traumatology Thoroughly revised and updated with a modern look and feel Eight new chapters on innovative developments in the field Contributions from world-renowned authors and editors Linked to www.dentaltraumaguide.org with a specific chapter on how the book complements the online guide This comprehensive textbook is an invaluable reference for undergraduate BDS courses worldwide, as well as a core text for postgraduate pediatric, oral surgery, and endodontics courses.
- By : J. R. Pinkham
- Medical
Pediatric Dentistry
Author: J. R. Pinkham
Publisher: Saunders
ISBN:
Category : Medical
Languages : en
Pages : 712
Book Description
This is a revised and updated A to Z guide to pediatric dentistry that defines the different management requirements of children at different stages of development. Material is presented within the context of four developmental stages : conception to age three, primary dentition years -- age three to six, transitional years from six to twelve, and adolescence. This 3rd Edition features three new sections covering dentistry for the child with special circ*mstances, understanding risk analysis as it effects diagnosis and treatment planning, and anticipatory guidance.
- By : Lari A. Bishop
- Corporations
Environment, Health, and Safety
Author: Lari A. Bishop
Publisher:
ISBN:
Category : Corporations
Languages : en
Pages : 50
Book Description
- By : Angus C. Cameron
- Medical
Handbook of Pediatric Dentistry E-Book
Author: Angus C. Cameron
Publisher: Elsevier Health Sciences
ISBN: 0702054283
Category : Medical
Languages : en
Pages : 512
Book Description
The new edition of this internationally recognised text offers comprehensive guidance on the successful management of the child in the dental setting. Prepared by authors of international renown, the Handbook of Paediatric Dentistry presents a volume that takes the reader far beyond the technical skills that are needed to treat disorders of the childhood dentition and instead delivers a whole philosophy of integrative patient care. Richly illustrated and in full colour throughout, the Handbook of Paediatric Dentistry is written in a friendly ‘how to’ manner and contains useful ‘pull out’ boxes to act as useful aide-mémoires. Exploring a variety of topics, the book includes discussion of child development, practical communication skills and advice on how to deal with behavioural problems. Clinical topics include the management of caries, fluoridation, restorative dentistry, pulp therapy, trauma management, oral medicine and pathology, dental anomalies, and the treatment of medically compromised children. Chapters also explore the use of orthodontics, the management of cleft lip and palate and speech, language and swallowing. The Handbook of Paediatric Dentistry has become an essential chairside and bedside companion for all practitioners caring for children and is suitable for undergraduate dental students, general dental practitioners, specialist paediatric dentists, orthodontists and paediatricians. Established as the foremost available comprehensive handbook on paediatric dentistry Prepared in an ‘easy-to-digest’ fashion – which allows for quick reference and easy reading Contains over 550 full colour line artworks, photographs and tables together with ‘Clinical Hints’ boxes to act as useful aide-mémoires Sets out the essentials for managing conditions such as clefting disorders, haematological and endocrine disorders, congenital cardiac disease, disorders of metabolism, organ transplantation and cancer in children as well as more familiar presentations such as dental trauma, oral infections and caries Detailed appendices provide the reader with information that is often difficult to find and which may be overlooked Designed specifically to give all practitioners confidence when managing children Convenient handbook size ensures that the book can be easily referred to in the clinical setting Endorsed by the Australasian Academy of Paediatric Dentistry ~ Improved layout and completely new colour illustrations Expanded section on sedation and use of nitrous oxide Includes details from the most recent international guidelines Cases expanded to show 20 year follow-up Includes the latest research findings in orthodontics Fully updated section on clefting problems
